CBD Dosage: How Much to Take?

CBD Dosage: How Much to Take?

As this article makes clear, many factors determine how much CBD oil is right for an individual. The elements start from a person’s biological constitution to the form in which they are taking their CBD. The condition for which they are taking the oil is also an important factor. What these variances mean is that there is no one-size-fits-all CBD dosage. If the user is under medication, they should seek the counsel of a physician in determining how much CBD and when they should take it. If, on the other hand, a person is using CBD for general wellness, they can start by taking small doses and work their way up until they find the dosage that works best for them.  

The Right CBD Oil Dosage: Factors to Consider

The Food and Drugs Administration (FDA) has only approved one CBD based medicine known as Epidiolex. This drug is prescribed for drug-resistant epilepsy. Having gone through all the trials and processes before approval, dosage guidelines for Epidiolex are well laid out and documented. The laying down of dosage guidelines is based on the fact that the drug is used for a clearly defined condition whose severity can be measured on a case by case basis. The unique parameters of the user can also be determined and how much CBD their body can handle determined.  

CBD oil is a different kettle of fish altogether. It can be used for a highly varied number of conditions, and it can also be used simply for wellness. Research on the oil hasn’t gotten to clinical trials, and people mostly use it as a supplement. This supplement status means that there are no clear guidelines on hemp oil dosage.  Let’s explore this issue together to find out which guiding principles one can apply to determine the right dosage.

Reason for its Usage and Other Drugs Being Used Alongside.

A person’s condition that leads them to take CBD plays a vital role in determining how much CBD they should take. Before we proceed, let us look at some of the conditions that taking CBD oil can help a person to manage.  

The conditions are as follows: high blood pressure, Alzheimer’s, Migraines, irritable bowel syndrome, withdrawal symptoms, rheumatoid arthritis, nausea, schizophrenia, and ADHD. Others include PTSD, anxiety, nausea, bacterial infection, diabetes, depression, bacterial infection, depression, acne, dyskinesia, psoriasis, broken bones, mad cow disease, inflammation, pain, Parkinson’s disease, ALS, MS, and epilepsy.

Equal amounts of CBD oil reduce the symptoms of these conditions to varying degrees. The question of dosage, therefore, can only be discussed based on the condition for which it is being used.

Besides the direct effect that CBD has on these conditions, there is the question of how it interacts with drugs prescribed for the diseases.

One of the consequences of using CBD is that it inhibits the activity of Cytochrome P450 Enzyme. This enzyme is commonly referred to as the (CYP450), and it originates in the liver. The protein is responsible for the synthesis of about 60% of all prescription drugs. This is a very significant percentage of drugs, and therefore, when CYP450 is not working to full capacity, some toxins from these drugs may find their way to the rest of the body. 

It is also noteworthy that some other ingredients that manufacturers commonly blend with CBD  have the same slowing effect on the liver. These additional ingredients with the same effect on the liver include watercress, St. John’s Wort, grapefruit, and goldenseal. When you have all of these ingredients working in concert in one CBD oil, they can significantly increase the time required for drugs to be synthesized. When CYP450 slows down, the liver is not able to metabolize medicine within the stipulated time. If such a scenario isn’t managed carefully a person might find themselves taking more medicine before the liver fully metabolizes the previous dose. This might lead to an overdose. 

A person’s dosage should be appropriately calibrated to avoid such an outcome if they are using CBD alongside pharmaceutical drugs. It can also mean that the user should take CBD within a certain length of time before taking the other medications so that its effects on the liver can be reduced by the time they take prescription drugs. 

The following are the drugs that CYP450 enzyme synthesizes; steroids, HMG CoA reductase inhibitors, antihistamines, calcium channel blockers, antiretrovirals, immune modulators, antiarrhythmics, prokinetics and benzodiazepines.  Others include, antibiotics, anesthetics, antipsychotics, antidepressants, anti-epileptics, beta-blockers, PPIs, NSAIDs, angiotensin II blockers, oral hypoglycemic agents, and sulfonylureas. 

Synthesis of the above drugs may be hindered by the wrong dosage and wrong timing in CBD use.

Besides slowing down the synthesis of toxins in the drug, CBD’s effects on the CYP450 pathway hinders prodrugs. Prodrugs are drugs whose active ingredients are only released after the drugs have been synthesized in the liver. Such a drug would have little to no effect on the user when the pathway is not working optimally. The condition for which the drug was being taken, therefore, may get worse if the dosage of CBD is not calibrated well enough to allow the liver to work effectively. 

With these factors in mind, it’s advisable to consult a doctor for advice on the recommended CBD dosage when a user is being treated with different drugs.  

Genetics and the User’s Endocannabinoid System.

The only reason why CBD affects our bodies is that we have the endocannabinoid system. The endocannabinoid system is made of three parts; the cannabinoid receptor, cannabinoids, and the metabolic enzymes. When a person takes CBD, it connects to the CBD receptors in the endocannabinoid systems, and it is from here that CBD Influences body systems in various ways.  The effectiveness of CBD receptors varies from person to person, and the more effective the receptors are, the higher the effects small amounts of CBD will have on the body.

Cannabinoid receptors are divided into two, CB1 and CB2 receptors. CB1 receptors are located in the Central Nervous System, while CBD2 are located in the rest of the body. So, where does genetics come in? The CNR1 gene is the one that codes the CB1 receptor. There are some people whose CNR1 gene has a mutation that causes the CB1 receptors to be less efficient in the absorption of CBD. For such people, a higher dosage of CBD would be required than in people whose CB1 receptors usually work.

Besides genetics, other factors affect the effectiveness of CB1 receptors. We have categorized them into factors that affect receptors positively, increasing the reception of CBD and those that affect them negatively, reducing the response of CBD. 


CBD Oil Dosage

Alcohol and weed: – Different drugs have different and often opposite effects on the CB1 receptors. The use of alcohol and recreational marijuana, for example, makes CB1 receptors more active. This means that, on average, people who smoke weed and those who drink alcohol feel the effects of CBD more quickly than those who don’t use either drug. 

The relationship between CBD and alcohol is made more interesting by the fact that CYP450 plays a vital role in the synthesis of alcohol. When a person is a casual drinker, the alcohol they take is broken down by a group of enzymes known as Alcohol Dehydrogenase (ADH) or Aldehydrogenase (ALDH). 

When, on the other hand, a person takes a lot of alcohol, the workload is too much for ADH and ALDH, and the CYP450 pathway of the liver has to take up alcohol synthesis. We have already mentioned that CBD slows CYP450 down. This means that the liver synthesizes ethanol more slowly when the drinker has taken CBD, and alcohol gets into the bloodstream more slowly, thus less drunkenness. This is how CBD helps people who are trying to heal from alcohol addiction. It reduces their motivation for a relapse. 

Exercise and an active lifestyle: – Exercise is another lifestyle choice that helps the body receive CBD better. This is because exercise increases the level of anandamide in the body. Anandamide is an endocannabinoid (cannabinoid that is naturally released in the body) that works more or less in the same way as THC. One of the roles of anandamide is to activate CB1 receptors, and a user’s CB1 receptors are, therefore, more receptive to CBD when there is high anandamide in the body. 

Diet rich in Omega 3 fatty acids: – CB1 receptors may be enhanced by high levels of omega-three fatty acids diet. In as far as lifestyle is concerned, it means that a person who takes fish, hemp seed oil, and other foods that contain high amounts of Omega 3 is more likely to feel the effects of CBD. A body that is more sensitive to CBD means that a person can take a lower dosage of CBD and feel the impact on the body more as opposed to a person whose Omega 3 intake is smaller, thus affecting the dosage.


Opiates: – Drugs such as morphine and epinephrine have been seen to reduce the activity of CB1 receptors.  The two drugs fall under the category of opioids. This effect means that a person who is using opiates may need higher doses of CBD oil to experience the same impact as someone who doesn’t use them.  

Stress and Depression: – Some hormones reduce the levels of CB1 in the body. Collectively, these hormones are known as glucocorticoids. A typical example of these hormones is cortisol, which the brain releases when a person is stressed. The practical application of this, in as far as the dosage of CBD oil is concerned, is that a person who is given to chronic stress has fewer CB1 receptors, and they, therefore, don’t synthesize CBD as efficiently. Seeing that many experts recommend CBD as a remedy for stress, anxiety, and depression, it is crucial the dosage for people with these conditions should be adjusted accordingly.

People with chronic diseases often have stress and depression as a result of their struggle with ill health. The CBD they get for the management of their symptoms should be determined with the effects of stress on CB1 receptors in mind.  


The right dosage for pharmaceutical drugs and supplements has always been different in men and women, and the case applies to CBD. There are physiological differences between the two genders that affect the way CBD interacts with their bodies.  

These physiological differences may be as simple as bodyweight – men are heavier than women on average. Like every other compound that the body metabolizes, people with less surface area to volume ratio require less than those who have higher SA/VR. Thus, on average, men require higher dosages of CBD for a similar effect than women.

Over and above weight, body chemistries of men and women are different. Differences in biochemistry and socialization make men and women susceptible to various diseases, which, in return, affect their CBD intake differently. For example, women are more vulnerable to depression, cataracts, IBS, MS, rheumatoid arthritis, among other diseases. CBD has been found to help manage symptoms in all of these conditions.

The effect of CBD, however, may be dampened by the results of some conditions on the user’s body chemistry. Depression, for example, comes with an increase of glucocorticoids such as cortisol, which reduces the effectiveness of CB1 connectors and thus reducing the efficacy of CBD. As much as this happens in all people with depression, it happens more often in women because more women get depression than men. In this case, the dosage should be relatively higher. 

Men, on the other hand, are more likely to use and abuse alcohol than women, and alcohol generally causes CBD receptors to be more active. Thus, the necessary dosage would be lower for such a person. Men also secrete more gastric acid, which causes their stomachs to be more acidic than women’s stomachs. When the stomach is too acidic, it inhibits the absorption of CBD. This affects CBD when it is taken in formulations such as edibles and capsules, which have to be swallowed. Tinctures, which people take sublingually go through the mucus membrane and directly into the bloodstream and gastric acid, therefore, doesn’t affect how much CBD is available to them.


Like everything else that goes into the body to affect it, the effect of CBD is felt depending on the amount of the said CBD per unit body weight. The more the CBD that gets into a user’s body, the higher the effect. Distribution of the CBD depends on the importance of the user, and therefore, heavier people require higher CBD doses than their lighter counterparts.


Manufacturers deliver CBD oil in different formulations, which have different methods of intake. Formulations include vapes, dabs, tinctures, capsules, topicals, among others. The dosage that would be effective in a tincture may not have the same effect when taken in the form of a capsule. The capsule has to go through the stomach and liver, a process that is generally not friendly to CBD due to acidity. The bioavailability of vapes is different from that of topicals due to the different methods of intakes.   We shall discuss the intake methods and factors affecting bioavailability in various ways further down.

Time Frame

This refers to the amount of time you have between taking CBD and feeling the effects. In some instances, people take CBD based on need, and they want to feel the results soon after. A good example is when the person is taking CBD to manage a panic attack. They take the oil as soon as they feel an attack is on the way. For CBD to be any help to them, it needs to work between the moment the person takes the CBD product and the time when a full-blown attack is expected. By acting within that timeframe, CBD will have succeeded in averting the crisis. Some studies have shown that, in some instances, up to 85% of CBD a person takes ends up not being utilized. With the question of bioavailability in mind, you need to take a higher dose to ensure that the required amount of CBD gets where it is needed quickly.


We have mentioned bioavailability in the course of discussing other factors, but it is worth a mention as an individual consideration. According to some studies, sometimes the CBD that a user’s body uses is as low as 5% of the CBD they take in. If this is the case, the correct dosage should be twenty times the amount the person needs to ensure they benefit optimally. 

Having noticed the dismal conversion of CBD in the bottle to actual benefits to the user, many manufacturers have taken steps to enhance absorption. There are some compounds they add into the CBD formulation for the sole purpose of making the CBD contained in those products more bioavailable. 

A good example is the carrier oil or base in a CBD oil.  There are many different carrier oils that manufacturers choose for various reasons. The reasons for selecting a particular oil over others may be the nutrients the carrier oils themselves have, its taste, and many other considerations. Still, increasing bioavailability of CBD is one of the greatest considerations. Common carriers include hemp seed oil, avocado oil, organic glycerin, and MCT oil. 

The effectiveness of carrier oils in providing bioavailability depends on the amount of saturated fats in it. Fats are central in this equation because CBD is fat-soluble, and the more the fat there is in the oil, the easier it is for the CBD to get into the body.

MCT oil, which is a coconut extract, is one of the carrier oils with the highest amount of fats, and it is, therefore, best placed to deliver CBD into the body. It follows, therefore, that dosage may be lower in an MCT base CBD product than in a, for example, hemp seed oil CBD product.

Besides carrier oil, innovative manufacturers usually infuse other ingredients that help improve the oil’s bioavailability. If capsules, which generally have meager absorption rates, are infused with Growth Cell Oligopeptide, it activates the endocannabinoid system around the stomach and increases the absorption rate by almost 100%. Other ingredients such as Fulvic Acid also help to increase the bioavailability of the product, and this lowers the necessary dosage. In light of this information, a user should seek to understand how much of the CBD in the product will eventually get into the body as a way of determining dosage and use the information to determine dosage. 


Tolerance refers to an individual’s ability to withstand the effects of a compound that gets into their body. People with higher tolerance require higher dosages for the compound to take effect when compared to people with lower tolerance. This tolerance can be natural or as a result of being exposed to a product for a long time.

A person establishes their natural tolerance level by taking the product and slowly increasing its dosage. One should increase the dosage until they get to a level where they can feel the maximum effects of CBD in their bodies.

The level of tolerance is usually determined by how well developed a person’s endocannabinoid system is. This level sometimes changes after a person has used a product for a while so that CBD potency that used to be effective on them ceases being effective. When that happens, the user needs to adjust their dosage accordingly. 

Besides adjusting the dosage upwards, some regular CBD users opt to stop using it for a while to give their ESC time to rest. When they resume, they will have reverted to the earlier effective dosage. This period of rest can be as short as 48 hours. 

Users can manage tolerance by using different products of the same potency separately for various durations of time. For example, a person can use CBD manufactured from hemp grown in Norway for three months and then switch to one whose hemp was grown in Tennessee for a few more months. When this happens, the person’s endocannabinoid system will connect differently with the CBD in these products because they come from different genetic strains of hemp. 

This routine can also be done with full-spectrum products, and CBD isolates from the same plant. The full-spectrum CBD products have other cannabinoids with which the ECS has to connect, while isolates only have CBD, and this keeps the ECS active, reducing tolerance.

Still, on tolerance, there is a phenomenon called reverse tolerance where, after using CBD for a while, the body requires lower CBD quantities to experience the needed response. This means that the dosage may be safely reduced. 

Remember that CBD is not Harmful.

CBD Oil Dosage

After looking at the above factors, you probably have noticed that there may be quite a bit of trial and error involved. This means that you may have to try the CBD product many times before you arrive at the right dosage for you. The question of whether CBD is harmful to your health and what taking it regularly during this trial period means to your health might have arisen in your mind. The good news is that CBD is unlikely to have the adverse effects people experience when dealing with other compounds. 

First, you need to know that CBD is not addictive. This doesn’t mean that the user can’t develop a dependency. A person may develop an addiction, but it is usually based on the condition the oil can alleviate. For example, if a person has arthritis, and they are in constant pain and CBD relieves that pain, they will feel the need for CBD when and after it wears off, and the pain comes back. There are also no withdrawal symptoms if you decide not to use CBD anymore. 

The body tolerates the compound well, and the fluctuations of intake during the trial period don’t affect the dosage you need to take either way. An excellent way to illustrate this is by using the example of antibiotics.

Taking lower or higher dosages of antibiotics is highly frowned upon. It is considered to be a highly reckless behavior because it caused disease-causing pathogens to develop tolerance to the active ingredients, and it may lead to a situation where the person has an incurable mutation of the disease. This is unlikely to happen to a person who is using CBD, and the ‘trial and error’ method of determining tolerance is therefore healthy. 

One of the main challenges with this reality is that if you don’t get your quantities right, you might end up using a lot of unnecessary CBD. This, as a result of the fact that the body will not give you negative feedback if you exceed the correct dosage. Seeing that CBD is not cheap, you end up spending a lot of money you shouldn’t be spending. In medical marijuana speak, you wouldn’t be getting enough ‘bang for your buck.’ 

How Much CBD Should I Take?

Considering the many benefits of using CBD, one can’t help but note that there are numerous gaps in information that shouldn’t exist. These gaps are because research on CBD and medical marijuana has been in the legal shadows for a long time. Currently, almost 60% of Americans live in jurisdictions where marijuana is legal, and this has created an enabling legal environment for research, much of which is currently ongoing.  

One of the consequences of this limited research is that it is difficult for people to pinpoint the amount of CBD they should take quickly. There are, however, some indicators you can use to help you come up with a dosage that suits you. It is also important to note that the level of tolerance varies widely. 

The first consideration is the disease for which you are taking CBD. One of the available guides was made by Mayo Clinic who sought to provide information to CBD users. The guide is as follows:- 

  • For inflammation in people with Alzheimer’s Disease – 160 mg 
  • For the reduction of pain in cancer patients, CBD can be combined with THC were on a ratio of 27mg THC and 25mg CBD.
  • The recommended dosage for anxiety is 2.5mg to 10mg. In comparison, panic attacks and phobias may be managed with high potency products of up to 600mg. Owing to cost, such high amounts of CBD should only be used as a regular dosage, and it is not sustainable. These super-high doses can also be delivered through dubbing.
  • People with schizophrenia can take an initial dosage of 1.5mg/day. This dosage is to be taken whether or not the person has an episode. A person may increase their intake in instances where the person is experiencing a psychotic break due to the disease.

If you compare the list of dosage developed by the Mayo Clinic, above and check it against it with the list of diseases that CBD can be used for provided earlier in the article, you notice that the dosage list only covers a small list of eligible conditions.  This is having not considered other non-therapeutic uses of CBD, such as its usage for general wellness. It is also true that these quantities are all indicative since a user’s body and severity of the condition they are treating also play a role in informing the ideal dosage.

So, how do you determine how much CBD you need when you have no reference? The quickest consideration is your weight. The heavier you are, the more the CBD you require even for purposes of general wellness.

The question of how much CBD you should take attains an entirely new level of importance when you are taking other medication. Earlier in this article, we discussed the effects CBD has on the CYP450 pathway and its role in the metabolism of drugs. It is, therefore, clear that you need the advice of a professional to determine your dosage in this case. Unfortunately, many doctors cannot make a precise determination of this matter, and you will need to look for one who has an understanding of CBD.

Other issues discussed earlier in the article under factors determining dosage also come into play in determining the dosage. Formulation of the product, for example, is a crucial determinant as you might find it necessary to take more CBD when using capsules than the amount you take in when vaping or using tinctures. The higher intake of capsules is because they don’t release CBD as efficiently into the body. 

How to Calculate CBD Dosage

If you are a CBD user with no other way to determine the dosage that is appropriate for you, you will need to calculate your dosage. Your body weight is the most crucial starting point. The right dosage, depending on your level of tolerance, is usually somewhere between 1mg and 3mg for every 10 pounds of body weight.

Thus, for a person weighing 200 pounds. The right dosage would range from 20-60mg per day. The best way to establish your level of tolerance is to start taking 1mg/pound and keep increasing as necessary until you get to a quantity that gives you the maximum benefit.

Let’s keep with the example of the 200 pound CBD user.

1mg/10 pounds for him or her add up to 20mg. Take 20 mg for a day or two and assess the impact. Increase to 2mg/10 pounds, which will be 40mg per day for two days and evaluate the effect. On the third attempt, increase the intake to 3mg/10 pounds, which will be 60mg of CBD and again assess the impact. You may keep going until you feel no additional effect even after increasing the dosage. When that happens, you should revert to the previous dosage as taking extra CBD without taking increased benefits would be wastage.

This dosage is only meant for a person who is taking CBD for general wellness. The dosage may vary if other variables, such as interaction with other drugs or symptoms that need to be treated, come into play.

It may be that you want to take CBD, not to experience its maximum effects, but to have a certain level of experience. You stop increasing your intake when you have taken enough CBD to attain the kind of impact you are looking for.

Go through this process of taking your CBD incrementally until you decide how much of it you need. You need to know how to determine the CBD quantity as you take it from your package. The manner in which you make this determination depends on the formulation you are using. 

Finding the amount of CBD in a bottle of oil:

Step 1: Determine the volume of oil in the bottle. 

For CBD tincture doses to be determined, one needs to be aware of the quantity of the bottle, concentration of CBD, and size of drops. Bottles usually come in different sizes, with the most common being 30ml. There are instances in which a manufacturer can package it in 10, 15, or 60mls. Volume is usually indicated on the product label

Step 2: Determine the amount of CBD in the oil.

The next thing after determining the volume is to figure out the concentration of the oil in the bottle. Strength varies widely from as low as 100mg to as high as 5000mg. When you have these two figures (volume and potency), you can calculate the amount of CBD in each ml of CBD oil or tincture. The total amount of CBD in each bottle is typically indicated on the label alongside the volume. 

Step 3: Work out how much CBD there is in each ml of oil.

You work-out the amount of CBD/Ml by taking the CBD in each bottle and dividing it by the volume of oil in mls. Thus if a container has 30ml of oil, and there is 100mg of CBD in the bottle, the CBD/ml of oil in that bottle is 3.3mg.

In a 30 ml bottle with 5000mg of CBD, on the other hand, the amount of CBD in a milliliter of oil is 166.7mg, which is more CBD than you get in some whole bottles of oil. The 5000mg potency bottle is probably not the right place to start taking due to its potency. It also doesn’t fall under the category of cheap affordable CBD oils.


The question, ‘how many drops of CBD oil should I take?’ Is answered by oil potency and droppers. CBD oils and tinctures typically come with droppers. Some manufacturers graduate these droppers at intervals of one or half ml. There are still other manufacturers who calibrate them in a manner that makes it possible to determine the volume of oil contained in each drop. You use the information you have about the quantity of each drop when ramping up your dosage.

When CBD oil is in formulations such as capsules, it is easier to determine how much CBD is in each helping. This is because the manufacturer indicates the potency. This same case applies to edibles such as CBD gummies and cookies. You know precisely how much CBD is in each of them.

There are other CBD products whose dosage is more difficult to determine than CBD oil. These are products such as vapes, hemp flowers, and dubs. While the amount of CBD in each is well indicated on the product label, it is difficult to know how much of it you take when you vape. It is due to lack of clarity in the amount of CBD you take in that such products are not recommended for use in determining dosage.

How to Take CBD

CBD Oil Dosage

Many nuances pertain to taking CBD.  In this section, we shall give you a brief guide on how to take CBD. Before we get into the discussion of how to take the product, we need to understand that the kind of CBD product you are using determines your method of intake. Tinctures, capsules, edibles, vape products, dabs, topicals, and pet products are some of the CBD products that are in the market today. The following are outlines of how you take CBD. 

Taking Edibles 

The word edibles refer to CBD products such as candy that you chew and swallow like everyday food items. Edibles mask the natural taste of weed with sugar, and they also contain preservatives. This is the reason why some people prefer them. These edibles are usually packed in pieces, and manufacturers typically indicate the amount of CBD there is in each piece. All one needs to do is to take the pieces whose content adds up to your recommended dosage and chew. 

While edibles are suitable for people who don’t like the taste of marijuana, they are unsuitable for anyone seeking to enjoy the benefits of CBD quickly. Their inability to act fast is due to the “first-pass effect.” CBD in edibles has to be broken down in part by the liver and also by the digestive system. This process of breaking it down is what is referred to as the “first-pass effect.” The entire process may take up to two hours and, even after that long, edibles only deliver about 30% of CBD into the body – on the higher side.

Taking CBD Sublingually

Taking CBD in sublingually refers to taking it under the tongue. The product that is best taken sublingually includes CBD lozenges, oral sprays, oils, and tinctures.

Taking CBD sublingually is advantageous due to its fast absorption. CBD gets into the blood through the tissue under the tongue, which can facilitate such absorption. If a person has panic attacks, they can take their CBD under the tongue when they feel signs of the onset of an attack.

This method would allow him to feel the effects of CBD within a minute and, in that way, avert a panic attack. Sublingual intake is quick because CBD doesn’t have to be broken down in the liver, and it, therefore, avoids the “first-pass effect.” Besides speed, this method typically avails more CBD to the user than the use of edibles. 

Concerning the bioavailability of CBD, it is essential to note that the carrier oil used in the oil is a crucial determinant. Those carrier oils that have a high content of saturated fats deliver more of the CBD into the bloodstream since CBD is a fat-soluble compound.  People who don’t like swallowing pills may find sublingual usage preferable. 

When taking tinctures and CBD oils, it is recommended that the user holds the oil under the tongue for one minute, after which they can wash down the remainder with water. In the case of lozenges, one should keep them under the tongue until they dissolve entirely, after which they can wash down whatever remains in the mouth with water or some other beverage.

Vaping, Dabbing and Smoking

Many different products use the intake mentioned above methods. They include shatters, certain CBD oils, and hemp flowers. Concerning smoking, the user should take CBD dominant hemp flower and roll it into a joint and then proceed to smoke it.

Habitual smoking is not advisable because all smoke contains some carcinogens that may lead to lung cancer and other types of damage to the lungs. 

Vaping requires the person to use a vape pen. One is required to refill a cartridge of e-liquid and then vape according to the type of vape pen they are using. While oils with many different kinds of products can be vaped, some can cause damage to the lungs, including some of the conventional CBD carrier oils. These include: –

  • MCT oil (Fractionated coconut oil)
  • Vegetable glycerin and 
  • Propylene glycol

Products that contain diacetyl, especially in flavoring, are not safe to vape because diacetyl causes popcorn lung. 

Dabbing refers to vaping CBD concentrates referred to as dabs. These dabs are in the form of shatter, crystals, and wax. They usually have exceedingly high purity levels that, at times, surpass the 99% threshold. Dabbing is, therefore, an effective way of taking in CBD. A person needs to use a unique device known as the dab tool. The precautions necessary in dabbing are more or less the same as those in vaping; to ensure that none of the additives that may be in the dab can negatively affect the lungs. 

All these three, related, methods of intake have one significant advantage. They deliver CBD quickly into the body, and they deliver up to 56% of it into the body. This is relatively better than other methods of intake. Once a person smokes, vapes, or dabs, they start feeling the effects within ten minutes.


These are products designed to deliver CBD into the body through the skin. They include balms, lotions, transdermal patches, balms, salves, and creams. They are ideal when a person wants to use CBD for localized pain such as joint pain caused by arthritis, or the inflammations one gets from sports injuries and other such events.

Topicals should be smeared directly on the user’s skin. They should never be ingested or applied to an open wound. Manufacturers usually blend other analgesics with CBD oil to enhance the power of these topicals. The most commonly used analgesics include menthol, capsaicin, eucalyptus, and camphor, among others. There are specific points to note when it comes to taking CBD through topicals. 

When CBD is taken by application, it isn’t subjected to the ‘first-pass-effect.’ The effect of CBD is likely to be felt faster, and the delivery is expected to be more efficient. The second important point to note is that the skin is far less permeable when compared to the sublingual tissue, which is a mucus membrane. With this in mind, the topical product one uses should be highly potent, and the user should also apply it copiously. Some manufacturers use compounds such as Pluronic Lecithin Organogel to enable CBD to penetrate the skin more easily. The creams that have such compounds are among the best CBD creams.  

Possible Side Effects

CBD is generally very well tolerated. It doesn’t have any psychoactive qualities, unlike its cousin, THC. Research on whether CBD has any side effects is still ongoing. There are, however, a few noticeable side effects that are noticeable. These include:-

  • Reduced alertness and drowsiness
  • Dryness of mouth occurs when CBD connects with the ECS on the sublingual salivary glands, thus inhibiting the production of saliva.
  • Some people may experience a change in their mood, becoming agitated and irritable.
  • The jury is still out on whether CBD can cause liver failure. What is known is that it affects how the liver metabolizes drugs in that it makes it slower. Whether there are factors that can escalate this effect leading to liver failure is a matter that is still under review.
  • There may be negative consequences of mixing CBD with other drugs such as antidepressants. Some people may lose control of some of their faculties if they mix CBD with antidepressants and alcohol. Such a situation may lead to injuries. 

It is advised that people shouldn’t operate machinery soon after taking CBD until they have grown accustomed to the effect CBD has on them. If they find that they experience drowsiness and reduced reaction time, they should adjust their schedules accordingly. 

Is It Possible to Take Too Much CBD?

It has been proven, scientifically, that human beings can consistently take doses as high as 1500mg daily and without too much trouble. Recent research, however, has raised some concern about the possibility of CBD causing liver failure, especially when taken alongside other drugs. 


As this article makes clear, many factors determine how much CBD oil is right for an individual. The elements start from a person’s biological constitution to the form in which they are taking their CBD. The condition for which they are taking the oil is also an important factor. What these variances mean is that there is no one-size-fits-all CBD dosage. If the user is under medication, they should seek the counsel of a physician in determining how much CBD and when they should take it. If, on the other hand, a person is using CBD for general wellness, they can start by taking small doses and work their way up until they find the dosage that works best for them.  

Dwight K. Blake Written by: Dwight K. Blake

Dwight was a Mental Health counselor at Long Island Psychotherapy & Counseling in Westbury, New York for more than 15 years. He believes that CBD is the prime solution to this mental illness and more-- with proper research, medical acknowledgment, and application.
Through his work at AmericanMarijuana, together with the rest of the team, he wishes to provide everyone with genuine results and high-quality product reviews for everyone to enjoy for free.

Leave a Comment

Exclusive Offer

25% OFF Free Ship

For All Orders Above $150

Editor's PickCBDistillery_1000MG_BSO_Tincture_UnitBox

Limited time offer


Use this code at checkout