Best CBD Oil for Anxiety and Depression: The Ultimate Buying Guide for 2019

Best CBD Oil for Anxiety and Depression: The Ultimate Buying Guide for 2019

I’m sure you’ll agree with me when I say this:

Finding a good CBD oil can take a lot of time, money, and hard work.

And if you’re like most people, you wouldn’t want to waste your resources going through hundreds of products. 

In this guide, you’ll learn all about the most reputable CBD brands on the market today – and everything you need to know to use CBD oil as a treatment option for your anxiety.

best overall


Runner Up


Best Flavored


NuLeaf Naturals
Most Potent

NuLeaf Naturals

Royal CBD
Best Value

Royal CBD

5 Best CBD Oils for Anxiety (Top Rated Brands)

  1. Best Overall Pick: Sabaidee 
  2. Runner Up: CBD Pure 
  3. Best Flavored: Fab CBD
  4. Most Potent: NuLeaf Naturals
  5. Good Value: Royal CBD

We regularly update this list with the best brands and latest discounts in an effort to save you money—so check back regularly.

Read detailed reviews of our top 5 best CBD oils for anxiety below:

1. Sabaidee


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In our opinion, Sabaidee is the best CBD oil for anxiety and depression. It comes from 100% organically grown hemp. Each bottle undergoes independent third-party lab testing to give you peace of mind when it comes to quality, purity, and effectiveness.

There are three options for you to choose from:

The Good Vibes 250mg+ is a good choice if you’re just new to using CBD products. It’s an all-natural, full-spectrum CBD hemp extract mixed with peppermint oil for flavor and MCT oil as its carrier.

Because it’s a full-spectrum CBD oil, you can also get omega fatty acids, vitamins, phytocannabinoids, and terpenes from it. The combination of all those components makes the oil more potent and effective.

Apart from the Good Vibes, Sabaidee also has the Super Good Vibes that pack about 33.5mg of CBD per dropper. This amount should be enough to provide relief to stress, pain, and anxiety.

Then, there’s the Mega Good Vibes that offers 88.33mg of CBD per serving. The high dose is excellent in providing relief from serious symptoms, making it a good choice if you’re planning on using CBD oil for panic attack.

2. CBDPure


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CBDPure is well-known for producing the high quality CBD products so it’s not really surprising how it earned a spot on this list. 

Its CBD oil has a golden yellow color since it’s processed through CO2 extraction. This method is the most commonly used means in extracting oil from organic hemp plant.

It’s also non-toxic which makes it the safest method around.

Apart from the color, another indicator of the quality of CBDPure oil is its flavor. It tastes a bit tart but since the oil passes through a filter, it tastes a lot better than other brands.

CBDPure uses only full-spectrum CBD which means that you’ll get additional cannabinoids to create that entourage effect. This makes the oil effective in providing relief not just from anxiety but chronic pain and sleep problems, too.

The oil comes in three different strengths. The lowest is the 100mg Pure Hemp Oil bottle which provides about 3.3mg of CBD per serving.

If that dose isn’t enough for you, there’s the option for you to go for the most potent option which is the 600mg Pure Hemp Oil. It should be able to give you about 20mg of CBD oil per serving.

3. Fab CBD


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Fab CBD Oil has a really impressive range of CBD tinctures. Currently, it has 4 available concentrations- 150mg, 300mg, 600mg, and 1200mg.

As each person reacts differently to doses and potencies, these concentrations enable you to find the best one that will work for you.

One of the nice things about this oil is that it comes in different flavors. While CBD oil doesn’t taste that bad, the additional flavoring makes it so much easier to consume. 

Now, don’t worry about the extra ingredients as the flavoring is made from all-natural sources. It won’t diminish the potency of the oil or cause any unwanted effects. It’s also non-GMO.

Fab CBD only uses all organic, industrial hemp for all of its products. They are also tested by a third-party lab to ensure that they can deliver their intended effects.

As for its effectiveness on anxiety, this CBD oil is actually impressive. It doesn’t just promote feelings of relaxation but it can also make you feel energized most of the time.

To give you an idea about how it’s processed, the oil actually undergoes a solvent-free CO2 extraction. It’s one of the newest and safest ways to process CBD oil.

4. NuLeaf Naturals

NuLeaf Naturals

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One of the things that set NuLeaf Naturals CBD oil from other brands is that it retains the additional compounds present in raw hemp source. This means that you won’t just get CBD, but you’ll also get vitamins and other phytocannabinoids.

The company uses hemp plants that are grown in Colorado farms. They are licensed and they follow sustainable farming practices which means that they don’t use any herbicides, pesticides, and other harmful chemicals.

All of their oils only possess trace amounts of THC or tetrahydrocannabinol to make sure that you don’t get high after consuming it. It’s also within the legally allowed level so you won’t get in trouble if ever you need to take random drug tests.

Their product lineup is quite impressive, too. There are options for those who require a small to really large CBD oil dosage for anxiety

5. Royal CBD

Royal CBD

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Royal CBD oil offers good value for money. Considering its concentration, amount, and the brand that created it, it’s surely worth every penny.

The oil is extracted using a process called CO2 extraction. After using pressurized carbon dioxide for the CBD extraction, it’s compressed and processed into a supercritical cold liquid state. They do all of those steps to preserve the nutrients of the oil.

Another thing to note about these oils is that they are submitted to strict laboratory testing to ensure that they are safe to consume. If any product fails to pass, it’s disposed of right away.

Considering that, there’s no chance for you to consume an oil filled with heavy metals and dangerous pathogens.

What Is Anxiety?

Anxiety is a normal human response to potentially harmful triggers. It initiates the “fight-or-flight” response where the body experiences a rush of adrenaline, increased sensitivity to the environment, sweating, and increased heartbeat.

When the anxious feeling gets out of proportion to the trigger, the anxiety progresses into an anxiety disorder. Once it reaches that stage, the anxiety has become severe enough that it interferes with a person’s daily function and mental health.

The Main Types of Anxiety Disorders

Anxiety disorders branch out to different types. The list includes:

Generalized Anxiety Disorder- This refers to a chronic disorder where people experience excessive and chronic anxiety about non-specific objects and life events. It’s considered to be the most common anxiety disorder.

Specific Phobias- These phobias create an intense fear about a specific situation and/or object. They often cause people to avoid ordinary situations out of fear.

Social Anxiety Disorder- This condition triggers an overwhelming worry about normal daily situations and interactions, particularly those involving other people. It causes a fixation on being embarrassed and judged.

Panic Disorder- This disorder strikes randomly. It causes sudden panic attacks that consist of one– or usually multiple– of the following: breathing difficulty, confusion, dizziness, shaking, nausea, and intense terror. It can last from minutes to hours.

Symptoms of Anxiety Disorders

While anxiety disorders can refer to different conditions, they share some common symptoms. Below is a quick list of their general symptoms:

  • Heart palpitations
  • Panic and uneasiness
  • Sleep issues
  • Inability to stay still and calm
  • Shortness of breath
  • Rumination
  • Dry mouth
  • Somatic complaints
  • Dizziness
  • Tense muscles
  • Feelings of dread

Using CBD Oil for Anxiety

cbd leaves

Managing anxiety is not as simple as it sounds.

For one, the cost of anxiety disorder medications is continuously rising. And of course, you’ll need to get those meds prescribed to you to begin with. For most people, they’ll have to pay a lot out of pocket even before their insurance covers a portion of it.

Plus, many medicines used to manage anxiety can cause a number of side effects. I won’t go into the details, but you’ve seen the ads where half of it is filled with side effects that are worse than what the medication is trying to solve.

Don’t get me wrong, if your meds are already doing well then don’t feel the need to make big changes. But some people either can’t take medications because of allergies or just don’t have bad enough anxiety to warrant seeking out medication.

This is why a lot of people turn to CBD oil for relief.

But here’s the question: Can CBD oil truly help ease anxiety?

The short answer is yes.

In fact, in many ways, it’s considered to be a better alternative to pills and shots for treating anxiety. Compared with those treatment options, CBD oil has a low risk of side effects and dependency.

How Does CBD Help You Deal With Anxiety

CBD regulates the body’s endocannabinoid system. It’s responsible for regulating the balance inside the body. It controls critical functions, such as immune responses, sleep, mood, and others.

When the body is in homeostasis, it’s able to function properly.

Anxiety is often a result of certain chemical imbalances in the body which is why finding a remedy that actually works can be both tricky and challenging.

This is where you’ll find CBD helpful.

Generally speaking, CBD is considered as a 5-HT1A agonist. In a simpler term, 5-HT1A works as a serotonin receptor. It’s often the target of SSRIs or Selective Serotonin Reuptake Inhibitors, a group of medications primarily prescribed for anxiety.

What SSRIs do is block the absorption of serotonin. This increases the ability of the brain to carry out more signals, improve mood, and lessen anxiety. CBD works in a similar fashion.

It can increase the signals to the serotonin receptors in the brain, boosting 5-HT1A transmission and improving mood quicker than conventional SSRIs.

And the best part?

CBD works just as well as traditional anxiety medications but without the nasty side effects.

What Research Has to Say

Over the years, there has been a lot of studies done to determine the effects of CBD and if it does work in easing anxiety and its nasty symptoms. 

For one, there’s this 2010 study that suggested cannabidiol’s capacity to lessen social anxiety symptoms in people diagnosed with social anxiety disorder. Apart from that, the same research also found out that the said substance changed the way its participants reacted to anxiety.

And then, there’s this 2014 study that showed CBD oil’s anti-depressant and anti-anxiety effects. Although it involved an animal model, the result revealed an interesting finding for humans.

In 2015, a report was published in Neurotherapeutics. The scientists involved in the said study were able to conclude CBD oil’s capacity to help in the potential treatment of post-traumatic stress disorder, panic disorder, obsessive-compulsive disorder, generalized anxiety disorder, and social anxiety disorder.

Clearly, most studies done on CBD oil showed how effective it can be in treating anxiety and minimizing its symptoms. However, as with anything you take for your health, it’s best if you can take the time to really know your options and determine what you’ll be taking for your body.

CBD oil is not regulated by the FDA in the United States, unlike your traditional anxiolytics. This means that there’s no solid way for consumers to actually know if the CBD oil they are using is pure or not.

You could be taking a CBD oil loaded with synthetic ingredients and you wouldn’t even know it. For someone who’s really having a hard time coping with anxiety, the effects of such ingredients can be difficult to fathom.

This is why you should take the time to really know your options. Check if the CBD oil you’re getting is safe, pure, and of high quality.

What to Look for When Choosing a CBD Oil for Anxiety

There are a couple of criteria you can use to check the quality of your CBD oil. Below is a quick overview:

Where the CBD oil is made

Choosing a company is critical in determining your CBD oil’s quality. You see, brands have different extraction methods and ways of processing CBD oil.

With that, you may want to research the brand’s production method. Find out how they are actually processing their oils. As much as possible, stick with brands that use CO2 extraction as it’s considered to be a safe and clean way of extracting CBD oil.

Hemp source

The cannabis plant has this ability to absorb anything that’s within its environment. So if you choose an oil that has been extracted from a hemp plant that grew in poor soil, the result will be unsatisfactory, too.

Third-party lab testing

A reputable CBD oil brand should have third-party lab results ready and accessible to its consumers. You can look for them in the packaging of your oil or the brand’s website.

How to Use CBD Oil for Treating Anxiety

As a first-time user of CBD oil to treat anxiety, you’re probably wondering how much to take to ease your condition. Well, the answer varies.

People react differently to CBD and how fast the oil works in easing the symptoms of anxiety will depend on the individual. Your height and weight are factors that need to be considered when determining the right dosage. Your existing medical conditions matter, too.

So, what’s the ideal dose?

There are no official guidelines but it’s best to start with a low dose. You can just build it up as you move forward.

For your safety, however, there are a few things you can consider:

  • Determine your height and weight. You also need to find out how severe your anxiety and symptoms are.
  • On the first day of use, start with a drop of CBD oil. This will give your body time to adjust to the CBD.
  • As you go along, increase your dosage slowly. Try adding 2 drops each day for a couple of weeks and see how that affects your symptoms.
  • Take note that it can take time for CBD to actually create dramatic changes in the way you feel. Wait a couple of days before increasing your dose.
  • Talk to your doctor before taking CBD for anxiety. This is to make sure that you’re not creating any negative reactions between your existing medications and the oil.
  • Based on a study on social anxiety, 600mg was an effective dose in reducing anxiety. However, there are also studies that suggest how taking lower doses can also improve the symptoms of anxiety.

The Risks of Taking CBD Oil in the Management of Anxiety

While CBD oil is considered to be generally effective in managing anxiety and offer tons of health benefits, it does entail a few risks and adverse effects.

One is taking it in a state that doesn’t approve it or considers it legal. 

Without regulation, you are increasing your risk of taking CBD oil that’s not guaranteed to be safe or free of contaminants. You could be exposing yourself to synthetic cannabinoids without even realizing it.

And that’s scary.

There are actually cases of acute poisoning from taking synthetic cannabinoids.

Apart from that, another risk in taking CBD is the interaction it causes when taken with other drugs. Like grapefruit juice, it can increase the level of coumadin in your blood which can predispose you to bleeding.


The use of CBD oil in managing anxiety is getting more and more common. With so many studies to back its positive effects on a person’s mental well-being, it’s not really surprising why.

However, despite the increasing demand for the oil and the suggested benefits of CBD, you should still exercise caution. Find high-quality CBD oil and make sure you know how much you should take and if you’re fit to include it in your treatment plan.

For us, our top pick is Sabaidee CBD Oil. Its impressive CBD oils are effective not just in managing anxiety but also in managing blood pressure, improving sleep, and controlling blood glucose levels. 

Learn more about them in our dedicated guides about best cbd oil for insomnia and best cbd oil for diabetes.

Now, if the taste of the oil bothers you, you can try other CBD products. You can try CBD gummies or you can look for vape products.

Go to Sabaidee by clicking the button below and enter coupon code AmericanMarijuana for 15% OFF

Dwight K. Blake Written by: Dwight K. Blake

Dwight was a Mental Health counselor at Long Island Psychotherapy & Counseling in Westbury, New York for more than 15 years. He believes that CBD is the prime solution to this mental illness and more-- with proper research, medical acknowledgment, and application.
Through his work at AmericanMarijuana, together with the rest of the team, he wishes to provide everyone with genuine results and high-quality product reviews for everyone to enjoy for free.

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