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Factors Impacting CBD Absorption and How They Impact CBD Absorption

How long does it take for CBD oil to work for pain relief? There is no short answer to this question. Read on to find out why. In general, the primary determinant of how fast the effects of CBD get felt in the body is the speed and rate of absorption.

Once CBD from the CBD oil has been absorbed into the body, it links up with the endocannabinoid system, and it starts working on the body. Understanding the factors impacting this absorption where your product is concerned is key to figuring out how fast your product can deliver CBD into the body.

The following are some of the factors and how they impact absorption.

Method of Consumption

The method of consumption is usually determined by the formulation of the CBD product being used. The path through which CBD passes to get into the bloodstream is an essential determinant for speed. Taking CBD Intravenously delivery is the fastest of enjoying its effects. Intravenous use is neither accessible nor comfortable for use on a day to day basis. It requires specialized skills, and it is, therefore, only used in the hospital setting under exceptional circumstances.

Just like intravenous delivery, the use of transdermal patches usually bypasses the first-pass process through the liver. This avails CBD to the body at a much slower rate but in a less controlled manner. The challenge with transdermal patches is low bioavailability, only a small percentage of the CBD in the product finds its way through the skin.

CBD tinctures are usually taken sublingually. The mucus membrane below the tongues allows it to dissolve directly into the bloodstream. This, in turn, allows for a quick uptake into the endocannabinoid system. Vaping and smoking deliver CBD through the lungs and onwards to the rest of the body. Inhaling CBD has been proven to be one of the most effective delivery methods in terms of bioavailability.

CBD products that require the CBD to be digested in the gut like regular food may have lower bioavailability. They include products such as CBD capsules. Edibles such as CBD gummies, cookies, and beverages also go through the same process. Their bioavailability is equally affected by the first-pass process. At their peak, oral CBD delivery methods tend to deliver less CBD than the other methods mentioned.

Carrier Oil

Once CBD has been extracted from industrial hemp or cannabis, it is mixed with a carrier. CBD is a fat-soluble compound and, therefore, oils form the best carriers for it. The higher the fat content in the carrier, the better it will be able to deliver CBD into the body.

Some of the common carriers include hemp seed oil, grapeseed oil, and MCT coconut oil, among others. The MCT oil contains more fat molecules, which makes it capable of dissolving and therefore delivering higher amounts of CBD than other carriers would.

The level of a CBD oil’s bioavailability, in turn, affects the speed with which effects of the oil can be felt. Lower bioavailability leads to a slower impact.

The User’s Weight

A person’s weight affects their response to virtually anything they take in – it is for this reason that doctors check a person’s weight before prescribing drugs. Weight impacts the effects of CBD because heavier people have more body fat. Body fat enables the user to retain the CBD in their body for long, which in turn allows CBD to be released into your system over a more extended period.

Effectiveness of the User’s Liver

CYP enzymes found in the liver play an essential role in ensuring that the CBD a person takes is broken down. They metabolize what the body needs for absorption and prepare excretion of what is not required.

If these hormones are incapable of working effectively, the excretion process isn’t as effective. This means that people with impaired liver function are likely to feel the effects of CBD more and for longer than people with better functioning livers.


The more the CBD is in a person’s body, the more it will be absorbed into their system. It, therefore, goes without saying that a person who takes a CBD product with higher potency will experience more of its effects and faster.

The dosage depends more on the potency of the CBD oil than on the amount a person takes. A more potent product delivers more CBD to the system. There are different types of products.

They include;

  • Full-spectrum products: These contain CBD and all other compounds found in the marijuana products from which the product was obtained. They provide the user with benefits from all other cannabinoids, but they may have a lower content of CBD.
  • Broad-spectrum products: These are just like their broad-spectrum counterparts, but they contain 0% THC because the manufacturers eliminate it. This is usually for the benefit of people who undergo drug tests regularly, and they can’t risk having even trace amounts of THC in their systems.
  • CBD isolates: These are products that contain nothing but CBD. Examples of CBD isolates include shatters, some of which contain up to 99% CBD. Smoking these shatters usually delivers exceedingly high dosages of CBD into the body.

Product Quality

The CBD industry is mainly unregulated in terms of quality. Thus, when buying CBD, you need to be careful to check for quality. Certain manufacturers have established a reputation for quality products, and you may be safer buying from them. Low-quality products usually contain additives and impurities, while high-quality ones seek to contain purer hemp extract.

One of the determinants as to whether the product is of good quality is the extraction method. Some extraction methods require the use of solvents to get the extract from the plant. This solvent is later distilled from the extract to purify it.

Sometimes the purification exercise isn’t thorough enough, and the product ends up containing traces of the solvent, and this lowers its effectiveness.

Some manufacturers include additives to the product for one reason or the other. These additives may end up reducing the quality.

How Fast Does CBD Oil Work?

The effects of CBD can start showing up in the body any time between a few minutes and six hours after use. As you can see, the difference between the shortest and longest possible time is massive. This makes it difficult to pinpoint the time at which an individual may feel the desired effects.

The only way to get a reasonable estimate is to examine it on a case by case basis. Two people taking the same amount of CBD would, in all likelihood, have different reaction times. A person can experience different reaction times at different times of taking CBD. Why would this be the case?

Many factors determine the speed of CBD’s effects on the body. These factors are usually related to the nature of the user’s body and the type of products they use. The following are some of the factors.

  • The potency of the product taken
  • Dosage used
  • Bodyweight of the user
  • Intended consequences
  • Consumption method

The first four factors play an essential role in determining how fast CBD works, but the consumption method is the most significant determinant. The following are some of the usual consumption methods.

Common Methods of CBD Consumption


This is, so far, the most common method of taking CBD. It refers to taking the CBD oil through the digestive tract. Once swallowed, the CBD product goes through the normal digestive process through the gut.

It then goes through the liver in the fast-pass process, where it is metabolized for use in the body. The first pass process takes time and effects of the CBD oil peak within one or two hours of taking it.

Through the first-pass process, the liver also regulates the amount of CBD that gets into the bloodstream. It does this by flashing out any amounts beyond what may be considered safe for the body to use. As a result of this, the effects of CBD are more subdued when it is ingested, but they are felt for longer.

A person who asks the question, ‘how long does it take for CBD oil to work for depression?’ May find that asking how long the effects of CBD remain in the body is a more relevant question for someone managing depression. The best CBD oil for anxiety and depression is the one that stays in the body for long.


You take CBD sublingually by allowing it to dissolve in the mucus membranes in the mouth, particularly the one under the tongue. CBD goes directly into the bloodstream without the first-pass process.

This means that you feel the effects of CBD faster, and the liver does not regulate the amounts, so you are likely to feel their effects more intensely. So, how long does it take for CBD oil under the tongue to work?  To take CBD sublingually, put it under the tongue and hold it for sixty seconds and then swallow whatever remains in the mouth.


Inhalation refers to smoking and vaping. The beauty with inhalation is that the effects of CBD kick in almost immediately. Inhalation also bypasses the first pass process, which means the amounts of CBD in the body isn’t regulated.

You can inhale CBD vapes oils, and CBD concentrates such, as shatters. CBD dominant buds are the only CBD product that is usually associated with smoking.


CBD topicals are the products applied on the skin, and they are then absorbed into the body through the skin.  At the skin, they connect with the endocannabinoid system and then affect the body in the manner they are expected to.

To get the best results, the user needs to account for the difficulty of getting CBD through the skin. They should, therefore, apply copious amounts of the product on the site where it is needed. This method is usually used for chronic pain, and the peak effect of the CBD is felt approximately 90 minutes after application.


The intravenous application gets CBD directly into the bloodstream. It is rarely used, and it is used only in hospitals. Users feel the effects of CBD immediately; it gets into the bloodstream, peaking within a few moments.

Key takeaways

The information above seems to provide information about humans. The answer to the question ‘how long does it take for CBD oil to work in dogs?’ is the same. It is imperative for anyone taking CBD to understand how quickly it will be of benefit to them. This is particularly important when it is intended to help the user manage an emergency.

The whole process boils down to the user’s physical attributes and the consumption methods used to take it. Even with these, an individual user must study their body’s response over time. The information they gather would then help them determine how to get CBD to work for them.